Fonte:Hospital de Clínicas de Porto Alegre • FAURGS • 2014
Questão 1954735
Acute Promyelocytic Leukemia (Acute Myeloid LeukemiaMM3) is characterized by its cytogenetic morphologic and molecular characteristics. Regarding this disease, consider the statements below. I M Cytogenetically is characterized by a balanced translocation between PML gen on chromosome 15 and the RARA α gene on chromosome 17. II M The underlying translocation t(15;17) leads to formation of the PMLMRAR and causes maturation arrest in the promyelocyte stage. III M Anthracyclines are associated to cytarabine t o improve complete remission rates in newly diagnosed patients. IV M Coagulopathy and hemorrhage are not seen in M3v subtype. V M ATRA (Trans Retinoic Acid) induces the differentiation of leukemic blasts into imature granulocytes. Wich ones are correct?
AOnly I, II and III.
BOnly I, II and V.
COnly II, III and IV.
DOnly II, III and V.
EOnly III, IV and V.
Revelar resposta correta
Resposta corretaAlternativa correta: B
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